Melee a God

Ares using the power Battle Titan

Taking on a Higher Power is no trifling matter.  It can be done, and has been done by mortals.  One of the few known successes is when Rax traveled to the home plane of Coeus and killed him.  Normally though, it takes a god to take down a god.  Besides the potential windfall of loot and magic items, it is more beneficial for a god to do it, because they can take claim to one of the dead god's domains.  For a god though, it is a very risky undertaking and normally only done if it is a sure thing.  If a group of mortals did decide to confront a god, they will need to be in the Epic levels, otherwise they have a near zero chance of success.  This is because all the statistics of the Higher Powers are very high and they have a number of traits that make unimaginably tough.  The two traits that are uniform across all higher powers are Modulating Energy and Divine Toughness.  The first is extra energy damage that they inflict with each damaging attack. For a Cult power, this is five hit points, but for a Greater power it is 25 HPS of damage with the energy type being whatever the victim is most susceptible too.  Divine Toughness is an increase in hit points that occurs at each power level.  This tops out at +8,000 hit points for a Greater power.  Higher Powers are formidable foes indeed, but not omnipotent or invincible - though any lay person would swear otherwise.  In the Demon Spawn War, a few Higher Powers fell forever.  Callarduran died battling Jurusalax and thirteen packs of runehounds of the largest size.   It was taking so long to bring him down, that Jurusalax had his hounds knock him down and then smother him.  If this had not been done, the health pool of Callarduran would have required an entire demon army to overcome.